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Gout .

Gout     Gout Patient.     Increase serum uric acid concentration  (Hyperuricaemia ) ● Recurrent attack of characteristics types of acute arthritis in which crystal of mono sodium urate monohydrate may be in leucocyte present in synovial fluid .. ● Deposition of monosodium urate mono hydrates in and around joints. ● Involvement of renal disease ● uric acid Nephrolithiasis . It is a disorder of purine metabolism manifested by follows features may occur singly or in combination.        Gout is a painful and potentially disabling rheumatic disease gout is characterised by high level of uric acid in blood . Uric acid is eliminate by kidney and passed out of body in Urine . If the kidneys are unable to eliminate uric acid efficiently blood uric acid levels will increase . ◆Clinically the natural history of gout comprises 4 stages 1 ) Asymptomatic Hyperuricaemia 2) Acute gouty Arthritis 3) Asymptomatic interva...

Tuberculosis

◆ Introduction :    Tuberculosis is the infectious disease . It is serious bacterial infection diease thats mainly affect the lungs. It is spread all over the World . It is as common as 1 million cases per year in india . As per survey In 2015 , 1.8 million people are died from TB with 10.4 million falling ill. ◆ Etiology ( causes) : It is caused by bacteria MYCOBACTERIUM TUBERCULOSIS (MTB)  . This is generally affect the lungs but can be affect all over the body it is known as Latent Tuberculosis. ● Mycobacteria are non motile ,non spore forming ,aerobic , facultative and measuring 0.2 -0.5 micrometer . By 2 -4 micrometer. Microbacterium Tuberculosis bactria ◆ Mode of transmission :  TB is spread through the air i.e droplet infection . From infected person to healthy person . A single sneeze can release upto 40,000 droplets , since the infectious dose of tuberculosis is very low so inhalation of only 10 bacteria cause an infection. ...

Parkinson's Disease .

"Parkinson's diesease  also know as idiopathic ,hypokinetic rigid syndrome . "It is a progressive neurodegenerative disorder , which result from degeneration of dopaminergic neurons in the Substantia niagra ,characterized by tremor,rigidity,and akinesha. The dieses is named after the English doctor JAMES PARKINSONS , who published the first detailed in Essay on Shaking Palsy in 1817 . ◆ Etiology   Damage of dopaminergic neurons, the Etiology of Parkinsons disease is still unclear , most cases are hypothesized to be due to combination of genetic and environmental factor . Currently known genetic causes of Parkinsons disease account for approximately 10% of cases ◆1) Environmental Cause Environmental risk factor commonly associated with the development of Parkinsons disease include use of pesticide , living in rular environment , consumption of well water , exposure of herbicide and proximity to industrial plants or quarries . ◆2) Genetic Fac...