"Parkinson's diesease also know as idiopathic ,hypokinetic rigid syndrome . "It is a progressive neurodegenerative disorder , which result from degeneration of dopaminergic neurons in the Substantia niagra ,characterized by tremor,rigidity,and akinesha. The dieses is named after the English doctor JAMES PARKINSONS , who published the first detailed in Essay on Shaking Palsy in 1817 . ◆ Etiology Damage of dopaminergic neurons, the Etiology of Parkinsons disease is still unclear , most cases are hypothesized to be due to combination of genetic and environmental factor . Currently known genetic causes of Parkinsons disease account for approximately 10% of cases ◆1) Environmental Cause Environmental risk factor commonly associated with the development of Parkinsons disease include use of pesticide , living in rular environment , consumption of well water , exposure of herbicide and proximity to industrial plants or quarries . ◆2) Genetic Fac...
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