Gout
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| Gout Patient. |
● Recurrent attack of characteristics types of acute arthritis in which crystal of mono sodium urate monohydrate may be in leucocyte present in synovial fluid ..
● Deposition of monosodium urate mono hydrates in and around joints.
● Involvement of renal disease
● uric acid Nephrolithiasis .
Gout is a painful and potentially disabling rheumatic disease gout is characterised by high level of uric acid in blood .
Uric acid is eliminate by kidney and passed out of body in Urine .
If the kidneys are unable to eliminate uric acid efficiently blood uric acid levels will increase .
Uric acid is eliminate by kidney and passed out of body in Urine .
If the kidneys are unable to eliminate uric acid efficiently blood uric acid levels will increase .
◆Clinically the natural history of gout comprises 4 stages
1 ) Asymptomatic Hyperuricaemia
2) Acute gouty Arthritis
3) Asymptomatic intervals of intestinal period
4) Chronic tophaceous gout .
1 ) Asymptomatic Hyperuricaemia
2) Acute gouty Arthritis
3) Asymptomatic intervals of intestinal period
4) Chronic tophaceous gout .
Normal serum uric acid
Male ♀ : 3.4 to 7.0 mg/dl
Female ♂: 2.5 to 6.o mg/dl
◆ Epidemiology
1) Gout is discovered by "Hippocrates".
2) Approximately 5% of all cases of arthritis
3) In Human it occurs about 840 people out of 100000.
4) Gout attack are also more common in people with kidney disease .
◆ Sign and Symptoms Of Gout .
1) High level of uric acid in blood .
2) Presence of uric acid crystal in joint fluid
3) the skin around an affected joint in red shiny and point and painful to touch .
4) Decomposition Of Uric acid crystal around joint and other areas such as the ear .
Male ♀ : 3.4 to 7.0 mg/dl
Female ♂: 2.5 to 6.o mg/dl
◆ Epidemiology
1) Gout is discovered by "Hippocrates".
2) Approximately 5% of all cases of arthritis
3) In Human it occurs about 840 people out of 100000.
4) Gout attack are also more common in people with kidney disease .
◆ Sign and Symptoms Of Gout .
1) High level of uric acid in blood .
2) Presence of uric acid crystal in joint fluid
3) the skin around an affected joint in red shiny and point and painful to touch .
4) Decomposition Of Uric acid crystal around joint and other areas such as the ear .
◆ Condition Which can proceed a Gout attack .
1) Dehydration
2) Injury
3) fever
4) Heavy alcohol intake
5) Recent surgery
6)Stress
1) Dehydration
2) Injury
3) fever
4) Heavy alcohol intake
5) Recent surgery
6)Stress
◆ Treatment Of Gout
1) Bed rest .
2) Low purine diet ( eat more fruit such as vegetable , grain, seeds and nuts .
3) Salicylate and or small doses of colchicine for the inter critic period .
Allopurinol ( zyloric) is very useful drug which reduces the synthesis of uric acid .
4) Indomethacin , Phenylbutazone can be used as alternative drug .
5) drink plenty of water
6) Exercise and weight loss.
7)Avoid stress.
1) Bed rest .
2) Low purine diet ( eat more fruit such as vegetable , grain, seeds and nuts .
3) Salicylate and or small doses of colchicine for the inter critic period .
Allopurinol ( zyloric) is very useful drug which reduces the synthesis of uric acid .
4) Indomethacin , Phenylbutazone can be used as alternative drug .
5) drink plenty of water
6) Exercise and weight loss.
7)Avoid stress.
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